无症状保留部分突出第三的患者的口腔微生物和全身脂质概况:初步的截面研究
Kamis Gaballah1,2, Priyadharshini Sekar2, Duaa Abuzayed1
1Department of Oral and Craniofacial Health Sciences, College of Dental Medicine, University of Sharjah, Sharjah, UAE.
International journal of dentistry
|December 1, 2025
概括
部分爆发的第三可能与高胆固醇和增加的Candida殖民性有关. 需要进一步的研究来证实这些关联,并了解保留的第三牙的炎症和代谢影响.
科学领域:
- 口腔健康和全身性疾病
- 微生物学 微生物学
- 心血管疾病的危险因素
背景情况:
- 部分喷发 (PE) 的第三可以引起局部炎症.
- 慢性炎症可能会影响诸如脂质样本之类的全身标志物,可能会增加心血管风险.
- 微生物殖民,包括细菌和Candida,可以加剧炎症.
研究的目的:
- 在PE患者中比较脂质样本和口腔微生物负担,与完全喷发的第三 (FE) 相比.
- 评估PE第三,脂质异常和全身炎症之间的潜在联系.
主要方法:
- 64名参与者 (20-35岁) 患有PE或FE第三的横截面研究.
- 测量了禁食脂质样本;通过qPCR分析了牙裂液 (GCF) 检测出Candida和细菌负载.
- 统计分析包括t测试和后勤回归.
主要成果:
- 在PE组中,总胆固醇 (TC) 升高的患病率较高 (15.63%),赔率比率 (OR) 为7.215 (p=0.051).
- 在PE部位的Candida存在量显著增加 (p=0.0036).
- 所有样本都存在细菌;然而,FE部位的细菌负载更高 (p=0.0066).
结论:
- 皮质前列腺第三可能与胆固醇升高和Candida殖民增加有关.
- 趋势表明,保留的第三牙可能具有潜在的炎症和代谢作用.
- 需要进一步的纵向研究来证实这些发现并澄清关系.
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