来自种子来源的人类食用的药用和食用草药的安全性:系统性审查
Lixia Yuan1, Bofei Shu1, Jieyi Zhou1
1Graduate School, Jiangxi University of Chinese Medicine, Nanchang, China.
Integrative medicine research
|December 1, 2025
概括
消费某些药用种子,如银杏和杏仁核可以引起不良事件,特别是在儿童和过量摄入. 这些种子的安全管理需要加强,以防止严重的结果和死亡.
科学领域:
- 药物监督 药物监督 药物监督
- 草药的安全性 草药的安全性
- 系统性审查 系统性审查
背景情况:
- 药用和食用种子被广泛使用,但它们对人类的安全性尚未得到充分评估.
- 这次审查系统评估了21种种子的安全性.
研究的目的:
- 综合评估21种药用和食用种子的人类安全数据.
- 识别具有显著不良事件 (AE) 概况和相关风险因素的种子.
主要方法:
- 对AE报告的英语和中文数据库进行系统的文献搜索.
- 包括在人类摄入特定种子后报告副作用的研究.
- 对AE特征和种子消费因果关系的评估.
主要成果:
- 在八种种子中确定了703个AE,其中金科种子和亚美尼亚种子 (Armeniacae semen amarum) 是导致最多的.
- 70.8%的AE发生在儿童中,68.9%与过量摄入有关.
- 严重的副作用包括15例死亡和3例永久性损伤,主要是来自银杏种和Armeniacae种子.
结论:
- 特定的药用种子存在风险,包括死亡事故,特别是过度使用或儿童.
- 银杏种子,亚美尼亚种子amarum,波斯种子,Myristicae种子和Canavaliae种子需要加强安全管理.
- 加强安全协议对于减轻与这些药用种子相关的风险至关重要.
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