世界各地的食物过敏严重程度:世界过敏组织的国际调查
Stefania Arasi1, Mário Morais-Almeida2, Bryan L Martin3
1Allergy Diseases Research Area, Pediatric Allergology Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
The World Allergy Organization journal
|December 1, 2025
概括
全球食物过敏的严重程度因地区而异. 世界过敏组织世界过敏组织
科学领域:
- 过敏和免疫学 过敏和免疫学
- 全球健康 全球健康
- 流行病学 流行病学
背景情况:
- 关于全球食物过敏严重程度的数据有限.
- 世界过敏组织 (WAO) 制定了对食物过敏严重性 (DEFASE) 评分的定义.
- 这项研究评估了DEFASE评分对IgE介导的食物过敏 (FA) 的全球适用性.
研究的目的:
- 为了评估WAO DEFASE得分的全球适用性.
- 评估全球IgE介导的食物过敏 (FA) 的严重程度.
- 探索FA管理和结果的区域差异.
主要方法:
- 一项国际在线调查 (WAO FASE项目) 被分发给WAO成员.
- 收集的数据包括诊断实践,治疗方法,患者特征,反应严重程度和引起剂量.
- 研究了FA管理成本,包括医疗费用和生活质量影响.
主要成果:
- 来自50个国家的157个中心的数据显示,FA管理的区域差异很大.
- 口服免疫疗法和奥马利祖马布在欧洲和北美更为常见.
- 在35%的患者中报告了严重的过敏反应症状,西亚和南非的发病率更高.
结论:
- 诊断和治疗机会的全球差异影响FA的严重程度和管理.
- 根据DEFASE评分,大约有3%的患者患有高度严重的FA,相当于严重的难治性喘.
- 医疗保健资源显著影响FA诊断和治疗的可用性.
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