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Updated: Jan 9, 2026

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Fosl1是BRAF驱动的V600E肠道瘤发生的转录效应体

Zakia Alam1,2, Rebecca Nightingale1,2, Analia Lesmana1,2

  • 1Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, Australia.

iScience
|December 1, 2025
PubMed
概括

Fosl1通过改变BRAF突变状瘤中的基因表达来驱动结直肠癌的进展. 这种转录因子由ERK信号激活,促进瘤生长和炎症,揭示了癌症发展的关键机制.

关键词:
生物科学 生物科学癌症 癌症 癌症 癌症基因调节的分子机制

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