饮食中的蛋白质摄入量与胆结石疾病之间的关联:一种病例对照研究
Amir Sadeghi1, Nastaran Raissi-Dehkordi1, Azita Hekmatdoost2
1Gastroenterology and Liver Disease Research Center, Research Institute for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Science, Tehran, Iran.
饮食中的蛋白质摄入量影响了胆结石疾病 (GSD) 的风险. 植物蛋白可能会防止GSD,而动物蛋白会增加风险. 适度的牛奶蛋白摄入量是有益的,但高摄入量可能是有害的.
科学领域:
- 营养科学 营养科学
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 饮食是胆结石形成的重要可改变的危险因素.
- 饮食中的蛋白质摄入量影响了胆结石疾病 (GSD) 的风险.
研究的目的:
- 调查不同饮食蛋白质来源与GSD风险之间的关联.
主要方法:
- 一项涉及189名GSD患者和342名对照者的病例控制研究.
- 评估饮食中的蛋白质摄入量是使用食物频率问卷进行的.
- 使用后勤回归模型估计赔率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 总蛋白质摄入量显示对GSD有保护作用,适度摄入比高摄入量更有益.
- 乳制品蛋白质摄入量与GSD风险呈现出U形关系;适度摄入量降低了风险,而较高摄入量增加了风险.
- 植物蛋白摄入量与GSD风险降低有关,而动物蛋白摄入量与风险增加有关.
结论:
- 饮食中的蛋白质,特别是来自植物来源的蛋白质,可以提供对GSD的保护.
- 动物蛋白质可能作为GSD的诱导因素.
- 适度的乳制品蛋白质消费有保护作用,但过度摄入可能会增加GSD风险.
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