左心房的全球应变支持左心房的终端-透缩体积,作为衡量左心房功能的指标
Sachiyo Igata1, Dwight Bibby1, Qizhi Fang1
1The Research Cardiac Physiology Laboratory, Cardiology Division, University of California, San Francisco, United States of America.
American heart journal plus : cardiology research and practice
|December 1, 2025
概括
左心房储压力 (LASr) 有效地测量左心房 (LA) 功能,在预测心血管事件方面反映了左心房末端透气体积指数 (LAEDVI). 这种心声回声测量为LA功能提供了有价值的见解.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏成像 - - 心脏成像
背景情况:
- 左心房末端透支体积指数 (LAEDVI) 是心血管事件的关键预测指标.
- 左心房储压力 (LASr) 是一种新的心声回声测量左心房 (LA) 功能.
- 该研究假设LASr在其预测能力上与LAEDVI平行.
研究的目的:
- 为了调查LASr和LAEDVI之间的关系.
- 评估LASr作为LA功能的潜在额外标记物.
- 评估LASr能够区分正常受试者,有心房风险的人和有心房史的人.
主要方法:
- 对133名来自BEAT-AFib研究的受试者和83名正常对照者的分析.
- 被试被分为正常,有风险的Afib和Afib组.
- 使用3D成像测量LA体积 (LAEDVI);通过2D斑点跟踪评估LASr.
主要成果:
- 与正常 (38%) (p < 0.01) 相比,LASr在有风险 (31%) 和Afib (23%) 组显著较低.
- 在风险组 (15mL/m2) 和Afib (21mL/m2) 组中,LAEDVI明显高于正常 (11mL/m2) 组 (p < 0.01).
- LASr与LAEDVI (r = -0.684),LAESVI (r = -0.528),LA喷射率 (r = 0.661) 和E/e'比率 (r = -0.571) (所有p < 0.01) 有显著的相关性.
结论:
- 在正常,有风险和Afib群体中,LAEDVI有显著的差异.
- 拉斯尔有效地区分了这些学科组,类似于LAEDVI.
- LASr 作为评估左心房功能的一个有价值的额外参数.
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