在卡布基综合征中增加严重外周动脉疾病的风险
Melissa Marie D'Andrea1, Luis R Leon2
1The University of Arizona College of Medicine, Tucson, AZ.
Journal of vascular surgery cases and innovative techniques
|December 1, 2025
概括
卡布基综合征 (KS) 患者可能会患上严重的外周动脉疾病,特别是在下肢. 血管内治疗被证明是安全有效的,用于管理这个具有挑战性的血管病变在KS患者.
科学领域:
- 遗传学 是一个遗传学.
- 血管医学 血管医学
- 儿科 儿科 儿科
背景情况:
- 卡布基综合征 (KS) 是一种罕见的遗传疾病.
- 癌症与先天性异常有关,包括器官功能障碍.
- 在KS中很少报告血管并发症,通常影响中央动脉.
研究的目的:
- 描述一个患有卡布基综合征的患者的外周动脉疾病病例.
- 评估KS下肢血管病变的管理方法.
- 为了强调这种罕见综合征中血管疾病的挑战.
主要方法:
- 一个被诊断患有卡布基综合征的患者的病例报告.
- 下肢外周动脉疾病的详细临床表现.
- 审查所采用的内血管管理策略.
主要成果:
- 患者出现了严重的,难以管理的下肢外周动脉疾病.
- 血管内管理成功实施.
- 这个案例说明了在KS中以前未经评估的血管表现.
结论:
- 周围动脉疾病是卡布基综合征的一个潜在的,具有挑战性的并发症.
- 内血管干预是一种可行的和安全的治疗选择.
- 对KS血管病变的开放外科手术技术的进一步研究是有必要的.
相关概念视频
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
326
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
326
Peripheral Artery Disease I: Introduction
290
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
290
Peripheral Artery Disease V: Postoperative Nursing Management
354
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
354
Peripheral Artery Disease IV: Nursing Management
321
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
321
Peripheral Artery Disease III: Interprofessional Care
226
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
226
Assessment of the Cardiovascular System III: Palpation
969
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
969


