相关实验视频
Updated: Jan 9, 2026

10:10
Reverse Total Shoulder Arthroplasty
Published on: July 5, 2011
43.8K
肝功能障碍与经过修复全肩关节整形术后的早期术后并发症有关
Steven H Liu1, Christian J Leonardo2, Joseph Kim2
1Department of Orthopaedic Surgery, Keck Medicine of the University of Southern California, Los Angeles, CA, USA.
Shoulder & elbow
|December 1, 2025
概括
亚斯巴胺转移酶与血小板比率指数 (APRI) 可以预测修复肩部全关节整形术 (TSA) 后的术后并发症. 肝纤维化和肝硬化增加了不良结果的风险,包括非家庭出院和肺炎.
科学领域:
- 整形外科手术 整形外科手术
- 肝病学 肝病学是一种肝病学.
- 手术结果研究研究.
背景情况:
- 修复全肩关节整形手术 (TSA) 存在术后并发症的风险.
- 酸氨基转移酶与血小板比率指数 (APRI) 是肝纤维化的非侵入性标志物.
- APRI对TSA修订后并发症的预测价值尚未得到充分确立.
研究的目的:
- 调查手术前APRI评分与手术后30天并发症之间的关联,在接受TSA修订的患者中.
- 确定APRI是否可以作为该患者群体中不良结果的预测指标.
主要方法:
- 对ACS-NSQIP数据库 (2015-2022) 进行了回顾性分析.
- 接受TSA修订的患者根据APRI被分为三个组:正常 (≤0.5),纤维化 (0.5-<1) 和肝硬化 (≥1).
- 后勤回归分析确定了30天术后并发症的独立预测因素.
主要成果:
- 患有APRI的患者表示纤维化,非家庭出院的可能性明显更高 (OR 2.28).
- 患有APRI表示肝硬化的患者面临肺炎 (OR 51.70),输血 (OR 4.52) 和深静脉血栓 (OR 23.91) 的风险增加.
结论:
- 术前APRI评分与TSA修订后的30天术后并发症有关.
- APRI可能有助于识别患有不良事件风险较高的患者,从而使有针对性的干预措施成为可能.
- 正如APRI所指出的,肝功能障碍是修复肩膀手术中显著的预后因素.
相关概念视频
Peripheral Artery Disease V: Postoperative Nursing Management
354
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
354
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
169
In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
169
Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow
203
Chronic liver disease significantly impacts drug metabolism due to alterations in hepatic blood flow and enzyme accessibility. This disruption affects the body's pharmacokinetics—the movement and processing of drugs within the system. Key enzymes crucial for metabolizing medications become less accessible, changing how drugs are processed and utilized. Furthermore, liver disease influences the synthesis of plasma proteins, such as albumin and globulins, which play critical roles in drug...
203

