运动对药物成患者执行功能的影响:系统性审查和三级元分析
Jiawei Chen1,2, Xuan Wang3, Xiaofei Zhang4
1School of Physical Education and Sport Training, Shanghai University of Sport, Shanghai, China.
Frontiers in sports and active living
|December 1, 2025
概括
炼可以显著改善药物成患者的执行功能 (EF). 有氧运动和综合训练显示出明显的益处,强调运动是这种人群认知增强的有效干预措施.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 康复医学 康复医学 康复医学
背景情况:
- 药物成与执行功能受损 (EF) 有关.
- 运动干预越来越多地被探索,因为它们有潜力减轻成中的认知缺陷.
- 在这个人群中了解运动对EF的有效性和调节者对于开发向治疗至关重要.
研究的目的:
- 系统地审查和元分析以运动为基础的EF干预措施对药物成患者的有效性.
- 确定影响该人口群体中运动-EF关系的关键调节因素.
主要方法:
- 我们对Embase,Scopus,PubMed和Web of Science数据库进行了系统的搜索.
- 包括的研究是随机对照试验 (RCT),评估了偏差风险.
- 使用R软件进行了三级随机效应元分析.
主要成果:
- 有906名参与者的11个RCT显示了整体EF (g=0.40) 和特定领域的显著改善:抑制控制 (g=0.25),认知灵活性 (g=0.58) 和工作记忆 (g=0.57).
- 有氧运动和与注意偏差训练相结合的有氧运动显示出显著的EF改善.
- 适度到剧烈的活动,每周5次,每次40分钟以上,以及12周的干预都与增强的EF相关.
结论:
- 运动是一种有效的干预措施,可以改善药物成患者的整体EF及其子域.
- 针对特定的EF子域和炼特征调节观察到的益处.
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