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A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening
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一种特定于Mycobacteria的原药,以克服Mycobacterium结核病中的表型AMR

T Anand Kumar1, Shalini Birua2, Sharath Chandra Mallojjala3

  • 1Department of Chemistry, Indian Institute of Science Education and Research (IISER), Pune, Maharashtra 411 008, India.

Journal of medicinal chemistry
|December 1, 2025
PubMed
概括

新的化乙原药有效地向低氧的Mycobacterium结核病 (Mtb). 这些酶激活化合物通过改善莫西弗洛克萨向不复制的Mtb的输送来克服耐药性,为结核病提供了一个有前途的策略.

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