过敏性鼻炎及其对喘的影响 (ARIA) -EAACI指南-2024-2025 修订:第一部分 - 鼻内治疗指南
Bernardo Sousa-Pinto1,2, Jean Bousquet3,4,5, Rafael José Vieira1,2
1MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
Allergy
|December 1, 2025
概括
新的指导方针建议在过敏性鼻炎 (AR) 治疗中使用鼻腔内皮质类固醇和抗胺组合. 这些更新的ARIA 2024-2025建议旨在通过指导鼻内治疗选择来改善患者的生活质量和生产力.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 药理学 药理学是指药理学的学科.
- 基于证据的医学基于证据的医学.
背景情况:
- 过敏性鼻炎 (AR) 显著影响日常生活和生产力.
- 移动健康 (mHealth) 数据提高了对AR的理解.
- 这些进展导致EAACI批准了2024-2025年过敏性鼻炎及其对喘影响 (ARIA) 指南的更新.
研究的目的:
- 提出ARIA 2024-2025指南对AR的鼻内治疗的建议.
- 为医疗保健专业人员和患者提供基于证据的指导,帮助他们选择合适的鼻内疗法.
主要方法:
- 使用GRADE证据决策框架制定了建议.
- 证据来源包括系统审查,移动健康数据,药物监督和专家成本调查.
- 十一个优先级的指导问题集中在AR的鼻内治疗选择上.
主要成果:
- 建议有利于固定的鼻内抗 ହି斯胺剂 (INAH) +鼻内皮质类固醇 (INCS) 组合,而不是单独使用INAH或INCS.
- 建议使用鼻内皮质类固醇 (INCS),而不是鼻内抗胰岛素 (INAH).
- 四个问题是新的,三个问题显示了建议强度或方向的变化.
结论:
- 在ARIA的2024-2025指南中,有助于选择AR的鼻内治疗方法.
- 治疗决策必须平衡临床变异性,患者偏好和药物成本.
- 这些建议支持患者,护理人员和医疗保健提供者有效管理AR.
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