膜组装了一个MAN1B1-VCP复合体,以向从内质网膜到溶酶体的外来糖蛋白,以降解

Jing Zhang1, Xiaoran Lu1, Sunan Li1

  • 1State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, 150069, China.

概括

门布拉林是一种新的ER-phagy受体,通过独特的途径向病毒葡萄糖蛋白进行溶酶体降解,增强先天的抗病毒防御能力. 这一过程将异物从宿主蛋白质中区分开来,独立于无处不在.

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