在侧面前极的威胁和可控性的综合表示
Joanne E Stasiak1,2, Jingyi Wang1,2, Neil M Dundon1,2
1University of California, Santa Barbara.
Journal of cognitive neuroscience
|December 1, 2025
概括
侧面前极 (FPl) 在预测威胁时整合情绪和控制信息,帮助目标导向的行动. 这个大脑区域的大脑区域.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 情感科学是一种情感科学.
背景情况:
- 情绪处理对于追求目标至关重要,无论是在当前情况还是未来的预期.
- 侧面前额皮质 (LPFC) 支持认知控制,侧面前端极 (FPl) 可能整合情绪和目标信息.
- 在需要采取行动的威胁预测期间LPFC的作用仍然不清楚.
研究的目的:
- 在威胁预测期间调查LPFC地区的动态参与和代表性质.
- 为了确定LPFC的组织属性是否在预测未来威胁时显而易见.
- 检查侧面前极 (FPl) 在整合情感和控制信息以实现目标指导的行动中的作用.
主要方法:
- 在fMRI数据上使用有限冲动响应建模和模式相似性分析.
- 健康的参与者 (n=67) 经历了与操纵的不愉快和可控性的威胁冲击范式.
- 检查了在威胁预测期间不同LPFC地区的参与和代表.
主要成果:
- LPFC强有力的编码预期的威胁不愉快性,FPl显示最强的调制.
- FPl表现出威胁和可控性的联动表示,与尾部/中部LPFC的独立编码不同.
- 较强的FPl连接表达与更好的运动性能和相反的杏仁体-FPl合相关.
结论:
- 在威胁预测期间,LPFC,特别是FPI,在整合情感和控制信息方面发挥着关键作用.
- 这些在FPI中的综合表示支持面临威胁的目标导向行动.
- 结果提供了对LPFC组织在自然主义情感挑战期间的见解.
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