Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Proteomics01:33

Proteomics

9.2K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
9.2K
Ribosome Profiling02:24

Ribosome Profiling

4.0K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
4.0K
Genomics02:02

Genomics

39.6K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Beyond Darwin: reactive heredity, burst-drift dynamics and eco‑evolutionary control of cancer.

Molecular cancer·2026
Same author

Cancer, collapse, and the politics of somatic evolution.

Evolution, medicine, and public health·2026
Same author

Predictive factors for injection interval extension after switching to faricimab in neovascular AMD: The FAR WEST multicentre study.

Acta ophthalmologica·2026
Same author

Toward next-generation machine learning and deep learning for spatial omics.

Briefings in bioinformatics·2026
Same author

Beyond immune privilege: the brain as a dynamic immunological interface.

Cell death & disease·2026
Same author

Lipidomic Insights into Seborrheic Dermatitis: Clinical Evaluation of Sebum Changes Using SpiderMass.

Dermatology and therapy·2026
Same journal

Biomedical Concept Recognition with Error-aware Negative-enhanced Ranking Framework.

Bioinformatics (Oxford, England)·2026
Same journal

TEDLH: Domain HMMs for sensitive detection of remote homologues.

Bioinformatics (Oxford, England)·2026
Same journal

PLNFGL: Joint Estimation of Multi-Condition Gene Networks from Single-cell RNA-seq Data.

Bioinformatics (Oxford, England)·2026
Same journal

MCFST: Spatial domain identification method based on multi-view graph convolutional network and graph fusion network.

Bioinformatics (Oxford, England)·2026
Same journal

SpaBiT: Enhancing Spatial Transcriptomics Resolution via Bidirectional Attention Transformers.

Bioinformatics (Oxford, England)·2026
Same journal

EDEL: Enhancing Dense Retrievers for Curation of Biomedical Knowledge Bases.

Bioinformatics (Oxford, England)·2026
查看所有相关文章

相关实验视频

Updated: Jan 9, 2026

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

12.6K

简介:一个开放的网络平台,用于多omics分析.

Yanis Zirem1, Léa Ledoux1, Isabelle Fournier1,2

  • 1Univ. Lille, Inserm, CHU Lille, U1192, Protéomique Réponse Inflammatoire Spectrométrie de Masse, PRISM, Lille F-59000, France.

Bioinformatics (Oxford, England)
|December 1, 2025
PubMed
概括
此摘要是机器生成的。

Profiler是一个新的开源平台,简化了复杂的多omics数据分析. 它整合了各种可重现研究工具,使先进的计算生物学可用于精准医学.

更多相关视频

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

2.0K
Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools
07:01

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools

Published on: August 19, 2025

773

相关实验视频

Last Updated: Jan 9, 2026

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

12.6K
Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

2.0K
Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools
07:01

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools

Published on: August 19, 2025

773

科学领域:

  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学
  • 系统生物学 系统生物学

背景情况:

  • 高通量多学科技术产生了大型的,异构的数据集.
  • 现有的生物信息学工具是分散的,阻碍了可复制性和可访问性.
  • 需要一个集成的,用户友好的,可扩展的平台来进行多omics分析.

研究的目的:

  • 介绍Profiler,一个开源的模块化平台,用于统一的多omics数据分析.
  • 为复杂的计算生物学任务提供一个用户友好的界面.
  • 为系统生物学和精准医学民主化多学科分析.

主要方法:

  • 简介:Profiler是一个基于Python的平台,使用Streamlit作为Web和桌面界面.
  • 它集成了数据导入,质量控制,预处理,统计测试,机器学习和深度学习.
  • 支持多种omics模式:蛋白质组学,转录组学,脂组学和电脑电图 (EEG) 数据.

主要成果:

  • 简介器在一个可重复的环境中统一了多样化的分析工作流.
  • 应用证明了分子亚型和潜在治疗点的可重复识别.
  • 快速生成完全可追溯的分析报告,用于质母细胞瘤和胰腺癌数据集.

结论:

  • 通过将高级分析集成到直观的界面中,Profiler使多omics分析民主化.
  • 它为系统生物学和精密医学研究提供了强大的,可扩展的基础.
  • 该平台提高了复杂的生物数据分析中的可访问性和可重复性.