探索怀孕期间和早期儿童神经发育期间母亲碳水化合物质量和数量之间的关系:在BiSC队列中进行的一项前性队列研究
Laura Panisello1,2,3, Javier Mateu-Fabregat1,2,3, Nil Novau-Ferré1,2,3
1Nutrition and Metabolic Health Research Group, Department of Biochemistry and Biotechnology, Rovira i Virgili University (URV), 43204, Reus, Spain.
European journal of nutrition
|December 1, 2025
概括
孕妇在怀孕期间摄入的碳水化合物会影响孩子的神经发育. 专注于低血糖指数 (GI),低血糖负荷 (GL) 和高碳水化合物质量指数 (CQI) 的食物可以支持更好的运动发育结果.
科学领域:
- 营养神经科学 营养神经科学
- 发育儿科 发育儿科
- 孕产妇健康 孕产妇健康
背景情况:
- 孕产妇的营养对胎儿神经发育至关重要.
- 碳水化合物摄入量,包括血糖指数 (GI),血糖负荷 (GL) 和碳水化合物质量指数 (CQI),在大脑功能中起作用.
- 了解这些关联可以为早期儿童发展策略提供信息.
研究的目的:
- 检查怀孕期间母亲的饮食碳水化合物摄入量 (数量和质量) 与幼儿时神经发育结果之间的关系.
- 评估GI,GL和CQI对儿童发育的影响.
- 确定潜在的饮食建议,以支持最佳的神经发育.
主要方法:
- 对1080对母子对进行前性队列研究.
- 在怀孕中期通过食物频率调查问卷评估母亲的饮食.
- 儿童神经发育在8,18和28个月使用标准化发育尺度 (DP-3,BSID-III) 进行评估.
- 用于分析的多变量线性回归模型,对共变量进行调整.
主要成果:
- 较高的母体碳水化合物摄入量,GI和GL与18个月后的语言和受体语言相反相关 (BSID-III),尽管在协变量调整后减弱.
- 增加的孕产妇GI和较低的CQI与18个月后较低的总运动分数有关 (BSID-III).
- 这些关联扩展到8个月和28个月的运动发育受损 (DP-3),特别是具有更高的GI和更低的CQI.
结论:
- 怀孕期间母亲的碳水化合物质量显著影响早期的神经发育,特别是运动技能.
- 在怀孕期间对低GI,低GL和高CQI碳水化合物来源的饮食重视可能会促进后代的积极发育轨迹.
- 进一步的研究可以阐明具体的机制,并完善饮食指南.
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