基于努力的共同决策范式的共同和独特特征及其与大脑结构和神经精神疾病的关系:综合叙事审查
Mario Bogdanov1,2, Diego A Pizzagalli3,4,5
1Center for Depression, Anxiety, and Stress Research, McLean Hospital, Belmont, MA, USA. mbogdanov1@mclean.harvard.edu.
Cognitive, affective & behavioral neuroscience
|December 1, 2025
概括
基于努力的决策研究使用各种方法,导致对大脑机制的不一致发现. 本综述阐明了这些范式,以提高对动机行为和临床应用的理解.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 行为经济学是一种行为经济学.
背景情况:
- 基于努力的决策 (EBDM) 范式通过检查成本效益分析来评估动机行为.
- 动机被概念化为衡量奖励与实现所需努力的过程.
- 在EBDM任务设计中的异质性使神经认知机制和临床发现的解释变得复杂.
研究的目的:
- 提供各种EBDM范式的全面概述.
- 讨论各种EBDM方法的优点和局限性.
- 整合关于EBDM神经相关物和临床影响的发现.
主要方法:
- 对广泛使用的基于努力的决策范式的文献综述.
- 对方法变化的分析,包括努力领域,奖励结构和时间组件.
- 综合研究神经基质和临床变化在努力估值的研究.
主要成果:
- 跨EBDM范式的方法异质性导致文献中的不一致性.
- 不同的EBDM任务揭示了努力估值的不同神经基质.
- 临床人群表现出改变了基于努力的决策过程.
结论:
- 标准化EBDM范式对于推进动机行为研究至关重要.
- 了解EBDM机制为神经精神疾病提供了洞察力.
- 为特定研究问题选择合适的EBDM范式提供了指导.
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