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Updated: Jan 6, 2026

Method for Measuring the Activity of Deubiquitinating Enzymes in Cell Lines and Tissue Samples
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Published on: May 10, 2015

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杜比基因酶OTUD5通过稳定YAP来促进硬度诱导的肝星细胞激活

Siying Jia1, Yongshen Niu1, Nafeisha Nuernijiati1

  • 1Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.

Molecular and cellular biochemistry
|December 1, 2025
PubMed
概括

矩阵刚性通过OTU二维基因酶5 (OTUD5) 和Yes相关蛋白 (YAP) 激活肝星细胞 (HSC). 这种OTUD5/YAP反循环驱动着结直肠肝转移的进展,提供了一个潜在的治疗点.

关键词:
肝脏的星状细胞是什么矩阵的刚度 矩阵的刚度在OTUD5中,我们可以使用OTUD5.瘤的进展情况.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈

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