用美国心脏协会的PREVENT评分来评估心血管风险预测的胆道生物标志物
Lidia Remolí-Sargues1, Clara Monferrer-Adsuara2, Belén López-Salvador1
1Department of Ophthalmology, Hospital Arnau de Vilanova, Valencia, Spain.
European journal of ophthalmology
|December 1, 2025
概括
心血管疾病 (CVD) 风险与胸腔血管成像中的变化有关. 较低的冠状腺区域和血管密度可能表明长期心血管疾病风险较高,这表明潜在的初级预防.
科学领域:
- 眼科医生 眼科 眼科
- 心血管医学 心血管医学
- 医疗成像医学成像
背景情况:
- 心血管疾病 (CVD) 风险评估模型如PREVENT对于初级预防至关重要.
- 冠状血管成像为全身健康提供了潜在的生物标志物.
- 心血管疾病风险和胆道血管参数之间的关系需要进一步研究.
研究的目的:
- 探索PREVENT心血管疾病 (CVD) 风险估计模型与胆道血管成像的定量参数之间的关联.
- 确定胆道结构和血管指标是否与估计的长期心血管疾病风险相关.
主要方法:
- 82名患者 (30-79岁) 的回顾性研究.
- 使用扫描源光学连贯断层扫描血管学 (SS-OCTA) 进行胆道血管度指数 (CVI),胆道总面积 (TCA),光线胆道面积 (LCA),筋胆道面积 (SCA) 和血管密度 (VD) 的定量分析.
- 基于10年和30年PREVENT分数的高风险和低风险组之间的参数比较.
主要成果:
- 在高危人群中观察到明显较低的TCA,LCA和SCA (p < 0.001).
- 在10年PREVENT得分和TCA,LCA和SCA之间发现了显著的负相关性 (r ≈ -0.350,p < 0.001).
- 在30年PREVENT评分和胆囊血管密度 (VD) (r = -0.370,p = 0.037) 之间发现了显著的负相关性.
结论:
- 冠状腺结构和血管参数显示与长期心血管风险的反向关联.
- 这些发现表明,胸腔成像在心血管疾病的初级预防中具有潜在的实用性.
- 为了验证这些结果,需要对更大的队列进行进一步的纵向研究.
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