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Updated: Jan 9, 2026

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CG-COA:用于系统的蛋白质-蛋白质对接验证的粗粒度立方方向方法

Zekeriya Duzgun1, Zuhal Eroglu2

  • 1Department of Medical Biology, Faculty of Medicine, Giresun University, Giresun, Türkiye; Department of Medical Biology, School of Medicine, Ege University, Izmir, Türkiye.

Journal of molecular graphics & modelling
|December 1, 2025
PubMed
概括

一种新的粗粒度立方方向方法 (CG-COA) 改善了灵活系统的蛋白质-蛋白质对接. 这种方法提高了适度灵活的蛋白相互作用的准确性,但对高度灵活或刚性接口有局限性.

关键词:
粗粒度分子动力学的粗粒度分子动力学灵活的蛋白质系统在MM/PBSA中,可以选择MM/PBSA.方法验证方法的验证方法.蛋白质与蛋白质的对接系统的定向采样采样

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