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Updated: Jan 9, 2026

Screening for Phytoestrogens using a Cell-based Estrogen Receptor β Reporter Assay
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通过雌激素受体通路对结构上不同 PFAS 的雌激素活性

Fanglin Hu1, Tingyu Lu1, Minjie Li2,3

  • 1College of Life Sciences, China Jiliang University, Zhejiang, Hangzhou, China.

Journal of applied toxicology : JAT
|December 1, 2025
PubMed
概括

这项研究揭示了包括 perfluorooctane sulfonamide (PFOSA) 在内的几个聚和 perfluoroalkyl 物质 (PFAS) 通过激活雌激素受体 (ER) 来表现出雌激素作用. PFOSA显示出最强的效果,强调需要评估PFAS超越PFOA,PFOS和PFHxS.

关键词:
雌激素受体的受体是雌激素受体.雌激素效应 雌激素影响在体外测定试验 (in vitro assays)分子对接的分子对接.perfluoroalkyl 化合物 是 一 种 不同 的 化合物 .

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