良性前列腺增生症患者的周围假肢关节感染:系统性审查和元分析
Antoninus Hengky1,2, Malvin Tandry2, Kevin Gracia Pratama2
1Center of Health Research, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Hip & pelvis
|December 1, 2025
概括
这项研究发现良性前列腺增生症 (BPH) 和周围假肢关节感染 (PJI) 之间没有显著联系. 需要进一步的研究来了解BPH患者对PJI风险的潜在间接影响.
科学领域:
- 整形外科手术 整形外科手术
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
背景情况:
- 周围假肢关节感染 (PJI) 是骨科手术的一个主要并发症.
- 良性前列腺增生 (BPH) 是一种常见的疾病,影响下部泌尿系统.
- 有人建议BPH和PJI之间存在潜在关联,但缺乏确的证据.
研究的目的:
- 调查良性前列腺增生症 (BPH) 与周围假肢关节感染 (PJI) 风险之间的关系.
- 通过元分析综合现有证据,以澄清BPH和PJI发病率之间的关联.
主要方法:
- 根据PRISMA 2020指南进行了系统审查和元分析.
- 在PubMed,EBSCO和ProQuest数据库中进行文献搜索.
- 来自五项研究的数据使用随机效应模型与综合元分析软件进行了分析.
主要成果:
- 分析显示,BPH和PJI增加的可能性之间没有统计学上显著的相关性 (OR 1.228,P=0.172).
- 对全关节整形术和全膝关节整形术的亚组分析也显示没有显著的关联.
- 没有证据表明BPH和PJI发病率之间存在直接联系.
结论:
- 良性前列腺增生 (BPH) 并没有直接与周围假肢关节感染 (PJI) 的风险增加有关.
- 其他因素,可能与BPH患者常见的感染有关,可能会影响PJI率.
- 需要进一步的研究来探索间接关系和混变量.
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