在不健康水平饮酒的艾滋病毒感染者接受和承诺治疗:ACCEPT随机对照试验的协议
Sarah E Woolf-King1, Emily Presutti1, Olivia McKenna1
1Department of Psychology, Syracuse University, Syracuse, NY, USA.
Contemporary clinical trials
|December 1, 2025
概括
这项研究测试了接受和承诺疗法 (ACT) 与艾滋病毒感染者不健康饮酒的短期酒精干预 (BI). ACT显示,在减少酒精使用和改善心理健康方面,有潜在的持续益处.
科学领域:
- 公共卫生 公共卫生
- 临床心理学 临床心理学
- 传染病研究 传染病研究
背景情况:
- 不健康的饮酒会对艾滋病毒治疗连续性产生负面影响.
- 接受和承诺治疗 (ACT) 和短暂的酒精干预 (BI) 正在与不健康饮酒的艾滋病毒感染者 (PWH) 进行比较.
- 接受试验 (NCT06648629) 调查了这些干预措施.
研究的目的:
- 为了比较ACT与BI在减少PWH中不健康饮酒的有效性.
- 评估这些干预措施对并发性精神病症状的影响.
- 探索体验性回避作为ACT的变革机制.
主要方法:
- 300名PWH报告不健康的酒精使用被随机分配1:1到ACT或BI.
- 评估包括自我报告和酒精生物标志物,用于酒精使用和精神症状.
- 在基线,治疗后以及3个月,6个月和12个月的随访期间收集的数据.
主要成果:
- 假设ACT和BI对治疗后和3个月的酒精使用产生同等效应.
- 假设在6个月和12个月的ACT的优异结果,通过减少经验性回避来调解.
- 探索ACT对抑郁,焦虑和压力症状的影响.
结论:
- 接受试验的结果可以为艾滋病毒治疗提供一种有价值的工具.
- 对不健康的酒精使用有效治疗也可以解决PWH的精神病并发症.
- 这项研究可能会改善对有物质使用和心理健康问题的PWH的综合护理.
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