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Updated: Jan 9, 2026

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通过Hsp90机器PINK1调节的分子机制

Xuyang Tian1, Jiayue Su1, Ziyi Wang1

  • 1State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, China.

Nature communications
|December 1, 2025
PubMed
概括

这项研究揭示了Hsp90及其合作伙伴如何调节PINK1,这是帕金森病中关键的蛋白质激酶. 低温EM结构显示了这一关键细胞质调节的分子机制.

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