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Updated: Jan 9, 2026

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从单独使用AlphaFold2的序列来快速估计蛋白质折叠途径.

Liwei Chang1,2,3, Alberto Perez4,5

  • 1Department of Chemistry, University of Florida, Gainesville, FL, USA. liwei.chang@schrodinger.com.

Nature communications
|December 1, 2025
PubMed
概括

AlphaFold2 (AF2) 隐式学习了蛋白质折叠原理,使其能够快速发现折叠路径. 在没有MSA的情况下运行AF2显示了折叠机制和中间结构.

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