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Updated: Jan 9, 2026

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
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Published on: April 2, 2012

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通过增加H3K9me3和ATRX的限制,在HSV-1神经潜伏期间通过干扰素依赖的免疫记忆

Abigail L Whitford1, Gaelle Auguste2, Alison K Francois1

  • 1Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA, USA.

Nature communications
|December 1, 2025
PubMed
概括

在初始疹简单病毒-1 (HSV-1) 感染期间的免疫信号创建了表观遗传记忆. 这种涉及ATRX的记忆限制了神经元中HSV-1的重新激活,从而提供了一个新的治疗点.

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