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Updated: Jan 9, 2026

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MCL1调节mTORC1信号,以促进生物能量和瘤发生

Wentao Gui1,2,3,4,5, Petr Paral6,7, Bhavuk Dhamija1,2

  • 1Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.

Nature communications
|December 1, 2025
PubMed
概括

骨髓细胞白血病-1 (MCL1) 蛋白质通过通过mTORC1信号调节新陈代谢来促进瘤. 氨酸补充剂可以通过恢复心脏mTORC1信号来降低MCL1抑制剂心脏毒性.

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