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Updated: Jan 9, 2026

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MYC驱动左撇子Z-DNA的形成,以塑造基因表达

Xinyi Wan1, Haonan Fan1, Zhuoning Li1

  • 1The Second Affiliated Hospital of Zhejiang University School of Medicine, Life Sciences Institute, Zhejiang University, Hangzhou, China.

Nature communications
|December 1, 2025
PubMed
概括

蛋白MYC招募FACT来诱导Z-DNA的形成,从而增强RNA聚合酶II的负载并促进转录. 这揭示了Z-DNA在基因调节和MYC驱动的癌症中的新角色.

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