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益生菌补充剂对更年期前和更年期妇女性功能的影响:一项随机对照临床试验

Roghayyeh Valizadeh¹, Fatemeh Borhani¹, Fatemeh Shabani¹

¹Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.

Scientific reports

|December 1, 2025

概括

益生菌补充剂显著改善了性功能,并提高了性功能障碍的妇女的生活质量. 这项研究强调了益生菌对女性性健康和整体福祉的潜在益处.

科学领域:

生殖健康生殖健康
微生物组研究微生物组研究
妇女健康妇女健康

背景情况:

性活动是女性生活质量的组成部分.
性功能障碍会对整体幸福感产生负面影响.
肠道微生物群在性健康中的作用是一个新兴的研究领域.

研究的目的:

评估益生菌补充剂对女性性功能的疗效.
评估益生菌对性功能障碍妇女生活质量的影响.
为了研究Lactobacillus acidophilus作为一种潜在的治疗剂.

主要方法:

这是一项双盲,随机,安慰剂对照试验,涉及64名绝经前和绝经后妇女.
参与者每天接受Lactobacillus acidophilus (3×10^9 CFU/cap) 或安慰剂,持续8周.
评估使用了女性性功能指数 (FSFI) 和更年期生活质量 (MENQoL) 问卷.

主要成果:

与安慰剂组相比,益生菌组的FSFI总得分明显改善 (P=0.038).
益生菌组的总MENQoL得分显著降低,表明生活质量有所改善 (P<0.001).
对于FSFI和MENQoL分数,研究小组之间没有观察到显著的基线差异.

结论:

摄入益生菌,特别是Lactobacillus acidophilus,可以提高女性的性功能.
用益生菌补充剂对经历性功能障碍的女性的生活质量产生了积极的影响.
建议进行进一步的研究来证实这些发现,并探索潜在的机制.

关键词:

乳酸菌酸性菌类的乳酸菌.更年期绝经绝经绝经前期的情况益生菌益生菌益生菌性生活性生活性生活性生活

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