身体圆度指数与老年患者骨质疏松症之间的关联:基于综合老年病学评估的横截面研究
Lingwei Li1, Yucen Ma1, Xinyi He1
1Department of Cadre Ward, The First Hospital of Jilin University, Changchun, 130021, China.
身体圆度指数 (BRI) 是老年人骨质疏松症的新型预测指标. 较高的BRI水平,特别是超过4.67的值,显著增加骨质疏松症的风险,突出其临床相关性.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 生物识别信息 生物识别信息
背景情况:
- 骨质疏松症是一种严重的与年龄相关的骨疾病,威胁着老年人的健康.
- 身体圆度指数 (BRI) 提供了比BMI更准确的身体形态评估,特别是对于腹部肥胖.
- 调查BRI与老年人骨质疏松症的关联对于公共卫生至关重要.
研究的目的:
- 研究住院老年患者的身体圆度指数 (BRI) 和骨质疏松症风险之间的关系.
- 探索潜在的非线性关联,并确定与骨质疏松症有关的BRI的关键值.
主要方法:
- 一项涉及620名老年患者 (≥60岁) 的横截面研究.
- 骨质疏松症通过超声波骨密度计诊断;BRI从腰围和高度计算.
- 多变量逻辑回归,受限立方线 (RCS) 和零碎逻辑回归被用于分析.
主要成果:
- 在BRI和骨质疏松症风险之间发现了显著的积极关联 (OR=1.587).
- 观察到一个J形的非线性关系,在BRI=4.67.7的断点.
- 在值以上,每一个单位的BRI增加,骨质疏松症的几率增加了178.9% (OR=2.789).
结论:
- BRI是老年人 (≥60岁) 骨质疏松症的独立人类预测指标.
- 确定了一个非线性J形剂量反应模式,具有关键值 (BRI=4.67).
- 在老年人群中,BRI作为骨质疏松风险分层的新生物标志物.
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