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炎症指数预测三膜手术后的早期结果不好:一项回顾性队列研究

Sanan Huseynov¹, Ali Bulut², Murat Kurtoğlu¹

¹Güven Hospital, Cardiovascular Surgery, Ankara, Türkiye.

|December 2, 2025

概括

术前和术后的中性粒细胞计数,中性粒细胞与淋巴细胞的比率 (NLR) 和全身免疫炎症指数 (SII) 可以预测三管置换 (TVR) 后的早期死亡率和并发症. 这些炎症标志物有助于风险分层和患者监测.

科学领域:

心血管外科心血管外科
炎症生物标志物炎症生物标志物
外科手术的结果

背景情况:

三巴置换 (TVR) 是一种关键的手术,可能导致早期不良后果.
准确预测TVR后的死亡率和并发症对于患者管理至关重要.
炎症标志物在TVR后预测结果中的作用需要进一步研究.

研究的目的:

调查中性粒细胞数,中性粒细胞与淋巴细胞比率 (NLR) 和全身免疫炎症指数 (SII) 在预测TVR后早期结果的预后价值.
评估这些炎症指数与住院死亡率和并发症的关联.

主要方法:

76名接受TVR的患者的回顾性分析.
术前和术后的中性粒细胞计数,NLR和SII的计算.
使用的接收器操作特征 (ROC) 曲线分析和考克斯回归模型.

主要成果:

住院死亡率为15.8%.
在非幸存者中观察到更高的手术前中性粒细胞计数,NLR和SII (P < .05).
术前和术后的NLR和SII在预测死亡率方面表现出高灵敏度和特异性. 手术前的中性粒细胞计数,NLR和SII是死亡率的独立预测指标 (HRs>1,P <.05).

结论:

中性粒细胞计数,NLR和SII是早期术后死亡率和TVR后并发症的显著独立预测因素.
这些炎症指数为增强心脏手术患者风险分层和术后监测提供了有价值的工具.
易于获取的炎症标志物可以改善TVR后患者的结果.

关键词:

发生并发症,并发症.死亡率死亡率作为一个中性恋者.中性粒细胞与淋巴细胞的比率.系统性免疫炎症指数三管门手术是三管门的手术.

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