小剂量西美西康和普罗纳斯溶液的前内镜饮料改善了上部胃肠内镜中的可视化:随机双盲实验
Yuan Li1, Jingping Jiang, Jinyi Sheng
1Division of Gastroenterohepatology, Department of Internal Medicine, The First People's Hospital of Jingde Zhen, Jingdezhen, Jiangxi, China.
Medicine
|December 2, 2025
概括
结合simethicone和pronase可显著改善在上部胃肠内镜 (UGE) 期间的可见性. 这种组合提供了一种安全有效的方法,用于增强UGE程序中的粘膜可视化.
科学领域:
- 胃肠病学 胃肠病学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 上部胃肠内镜 (UGE) 对于诊断胃肠疾病至关重要.
- 高质量的可视化对于准确的UGE发现至关重要.
- 研究改善UGE期间可视化的方法很重要.
研究的目的:
- 为了比较小剂量西美西康加普罗纳斯在UGE期间改善粘膜可见性的有效性.
- 评估前期治疗对UGE可视化质量的影响.
主要方法:
- 一项随机研究涉及400名接受UGE的患者.
- 患者被分为四组,在手术前15-30分钟接受迪克隆因,单独西米西康,单独普罗纳斯溶液或西米西康加普罗纳斯溶液.
- 记录了粘膜可见性和全粘膜可见性得分 (TMVS),较低的得分表明粘膜更干净. 此外,还对不良事件进行监测.
主要成果:
- 与迪克隆因 (D组),单独的西米西康 (S组) 和单独的普朗酶 (P组) 相比,西米西康加普罗纳斯 (P+S组) 的组合显示出明显更好的TMVS.
- 与D组 (6.76 ± 1.58),S组 (5.61 ± 0.91) 和P组 (6.46 ± 0.82) (所有P<.05) 相比,P+S组的TMVS得分明显较低 (4.91 ± 0.99).
- 在单独使用双克隆因 (D组) 和单独使用前酶 (P组) 组之间没有观察到TMVS的显著差异.
结论:
- 小剂量的西美西康和普罗纳斯溶液有效地提高了UGE期间的粘膜可视化.
- 西美西康和普罗纳斯的组合是一种安全有效的前期治疗,可以改善UGE的质量.
- 这种方法为提高上部胃肠内镜的诊断准确性提供了有益的选择.
关键词:
迪克隆因 (Dyclonine) 是一种通过内镜检查 (endoscopy) 进行内镜检查预先医疗是一种预先医疗.这就是说, pronase pronase.赛米西康尼 赛米西康尼 赛米西康尼更多相关视频
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