2型糖尿病的美国参与者中,甘油三糖-体重指数和喘之间的关联:一项观察性研究
Shengjia Zheng1, Minghe Wang, Yi Fang
1Department of Respiratory and Critical Care Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
高甘油三糖糖体质指数 (TyG-BMI) 与美国2型糖尿病 (T2D) 成人的喘风险增加有关. 管理新陈代谢健康是预防和管理喘的关键.
科学领域:
- 代谢健康 代谢健康
- 心血管疾病风险因素 心血管疾病风险因素
- 呼吸道疾病 呼吸道疾病
背景情况:
- 2型糖尿病 (T2D) 是一个日益严重的公共卫生问题.
- 喘影响了成年人口的很大一部分.
- 代谢因素和喘之间的关系需要进一步研究.
研究的目的:
- 调查甘油三糖-体重指数 (TyG-BMI) 与美国2型糖尿病成年人喘患病率之间的关联.
- 为了确定TyG-BMI对喘风险的潜在值效应.
- 探索这个协会中的子组变异.
主要方法:
- 利用了2005年至2016年国家健康和营养检查调查 (NHANES) 的数据.
- 包括3236名美国成年人,年龄大于20岁,已被诊断为T2D.
- 使用统计分析,包括非线性和子组分析,以评估TyG-BMI和喘关系.
主要成果:
- 在T2D患者中观察到TyG-BMI和喘风险之间存在显著的非线性关联 (P=0.016).
- 确定TyG-BMI值为208.96;超过这个值与每10个单位的喘风险增加5.4%相关 (OR=1.054,P<0.001).
- 这种关联在各种人口群体中保持一致,特别是在老年人 (≥65岁) 中.
结论:
- TyG-BMI作为评估美国T2D成年人中喘风险的重要指标.
- 在这种高风险人群中,代谢控制对于预防和治疗喘至关重要.
- 需要进一步研究TyG-BMI作为糖尿病患者呼吸系统疾病的预测标志物.
更多相关视频
08:30Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
Published on: March 15, 2018
06:13Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Symptoms, Diagnosis, and Complications
Obesity
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
