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新型2-pyrazoline-1-carboxamides作为抗阿尔茨海默症药物的合成,生物评估和分子对接

Fatih Tok1, Funda Aleyna Özer2, Zeynep Sude Kuzu2

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Marmara University, İstanbul, Türkiye.

Future medicinal chemistry
|December 2, 2025
PubMed
概括

新的酸衍生物显示出作为阿尔茨海默病治疗的前景. 这些化合物表现出强烈的抗氧化和胆酶抑制作用,其中一种化合物显示出穿越血脑屏障的潜力.

关键词:
模拟MD的模拟方法皮拉索林 (Pyrazoline) 是一种酸盐.这是一种抗阿尔茨海默氏症的药物.抗氧化剂是一种抗氧化剂.分子对接的分子对接.

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