在真菌顺序Sordariales中的全基因组编码子使用偏差的模式和驱动因素
Noah Hensen1, Markus Hiltunen Thorén1,2, Hanna Johannesson1,2
1Department of Ecology, Environment and Plants Sciences, Stockholm University, 11418 Stockholm, Sweden.
概括
索达里亚类真菌表现出子使用偏差 (CUB) 的变化,首选的是GC终结的子. 在Chaetomiaceae和BLLNS群体中,CUB的较高表明更强的选择,可能是由于利基专业化.
科学领域:
- 菌类学 菌类学是指菌类学.
- 基因组学就是基因组学.
- 进化生物学 进化生物学
背景情况:
- 菌类基因组表现出子使用偏差 (CUB) 的变化.
- 在Sordariales中,GC终结的编码体通常比AT终结的编码体更受青.
- 在Sordariales的不同真菌家族中,CUB的强度有所不同.
研究的目的:
- 为了研究氨基酸组成,代使用偏差 (CUB) 和Sordariales真菌中的选择压力.
- 为了在Sordariales顺序内的不同家族中比较CUB水平.
- 探索CUB中观察到的差异的潜在驱动因素.
主要方法:
- 分析了来自各种Sordariales家族的基因组数据.
- 评估氨基酸组成和子使用模式.
- 基因组聚类以确定进化关系.
- 评估自然选择对子使用的影响.
主要成果:
- 所有Sordariales的基因组都显示出对GC终结的编码子的偏好.
- 在Podosporaceae和Sordariaceae中,表现出较低的基因组范围的CUB.
- 沙托米亚科和BLLNS群体在全基因组中显示出更高的CUB,表明更强的选择.
- 基因组聚类揭示了Podosporaceae和Sordariaceae是密切相关的.
结论:
- 代使用偏差 (CUB) 的强度在Sordariales家族中不均.
- 在Chaetomiaceae和BLLNS中,较高的CUB与增加的自然选择有关.
- 生态利基专业化可能会在Chaetomiaceae中推动更高的CUB,与一般主义物种形成鲜明对比.
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