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Updated: Jul 18, 2026

Analyzing the α-Actinin Network in Human iPSC-Derived Cardiomyocytes Using Single Molecule Localization Microscopy
07:02

Analyzing the α-Actinin Network in Human iPSC-Derived Cardiomyocytes Using Single Molecule Localization Microscopy

Published on: November 3, 2020

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在动态机械基板上的受损瘤重组易患心肌病的人类iPSC衍生的心肌细胞

Nhu Y Mai1,2, Xiangjun Wu1,2, Huiyao Liu1,2

  • 1Department of Biomedical and Chemical Engineering, Syracuse University, 318 Bowne Hall, Syracuse, NY 13244 USA.

Cellular and molecular bioengineering
|December 2, 2025
PubMed
概括

在BAG3 (Bcl2-关联的乙醇基因3) 中的遗传缺陷会在机械应力下恶化心肌细胞损伤. 这项研究表明,BAG3缺乏的心脏细胞有肌纤维组织受损,影响扩张性心肌病的收缩功能.

关键词:
活跃生物材料 活跃生物材料疾病建模 疾病建模动态机械生物学 动态机械生物学人类诱导的多能干细胞干细胞.

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High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers14:03

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