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Updated: Jan 9, 2026

Precise Phage Mutagenesis with NgTET-Assisted CRISPR-Cas Systems
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缺陷补充同源重组:一种用于精确基因组工程的新策略,用于毒性菌体

Hailin Zhang1,2, Yueyue Song1, Wenyue Liu1

  • 1School of Life Sciences, Jining Medical University, No. 669 Xueyuan Road, Donggang District, Rizhao, Shandong Province, 276826, China.

Synthetic and systems biotechnology
|December 2, 2025
PubMed
概括

一种名为缺陷补充同源重组 (DCHR) 的新方法精确编辑菌体基因组,克服了开发用于细菌感染的工程菌体的局限性. 这一进步使得治疗应用的菌体能够有效地进行基因改造.

关键词:
克雷洛克斯 (Cre-lox) 是一个植物.基因补充是一种基因补充.同类的重组组合.菌体的遗传操纵 菌体的遗传操纵菌体基因组工程 菌体基因组工程

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