年轻成年人药物使用趋势和COVID-19大流行影响
Meital Zur1,2, Avishai M Tsur2,3,4,5, Limor Friedensohn2,3,6
1Pharmacoepidemiology Research Lab, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Pharmacoepidemiology and drug safety
|December 2, 2025
概括
COVID-19大流行改变了年轻人的药物使用,增加了吸入剂,抗抑郁药和避孕药,同时减少了抗菌药,抗腹药和ADHD药物. 这凸显了大流行对各种药物趋势的影响.
科学领域:
- 流行病学 流行病学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 随着COVID-19大流行,医疗保健系统和药物使用发生了重大破坏.
- 有限的纵向数据存在于疫情期间和之后年轻成年人的药物使用趋势.
研究的目的:
- 分析COVID-19大流行之前,期间和之后的年轻成年人药物开放趋势.
主要方法:
- 以色列国防军人员的基于人口的回顾性队列研究 (2017年1月-2023年8月).
- 使用通用线性模型来评估月度发行率的中断时间序列 (ITS) 分析.
- 疫情前的数据确定了基线趋势;对疫情期间产生了反事实预测.
主要成果:
- 在疫情前,上腺激素吸入剂,抗腹药和多动症多动症药物显示出日益增长的趋势.
- 在大流行期间,上腺激素吸入剂,抗抑郁药和激素避孕药的开放量增加.
- 相反,抗菌,抗腹和ADHD药物处方在大流行期间下降.
结论:
- 药物使用模式在大流行期间发生了变化,可以根据它们与大流行原因,症状或社会破坏的关系来分类.
- 研究结果为预测和管理未来流行病期间的药物需求提供了一个框架.
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