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在原发性Sjögren综合征中失调的血细胞状树突细胞:正常功能但数量减少

Rongli Li1, Yimeng Jia2, Xunyao Wu3

  • 1Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing; and Department of Rheumatology and Immunology, the First People's Hospital of Yunnan Province, the affiliated Hospital of Kunming University of Science and Technology, China.

Clinical and experimental rheumatology
|December 2, 2025
PubMed
概括

血细胞状树突细胞 (pDCs) 在初级Sjögren中减少.

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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