母亲神经性厌食症和子女精神和神经发育疾病的风险
Sam Amar1, Gabriel Côté-Corriveau2,3, Mimi Israël4
1Faculty of Medicine, McGill University, Montreal, QC, Canada.
Child and adolescent mental health
|December 2, 2025
概括
患有神经性厌食症的母亲的孩子面临精神,物质相关和神经发育障碍的风险增加. 对母亲的早期心理社会支持可能有助于预防这些儿童疾病.
科学领域:
- 儿童心理学 儿童心理学
- 孕产妇健康 孕产妇健康
- 神经发育障碍 神经发育障碍
背景情况:
- 母亲的神经性厌食症可能会影响胎儿的神经发育.
- 这项研究调查了母亲的精神性厌食症与后代的精神,与物质有关的和神经发育健康之间的联系.
- 了解这些关联对于早期干预和支持至关重要.
研究的目的:
- 检查母亲神经性厌食症与儿童随后的精神,物质相关和神经发育疾病之间的联系.
- 量化与母亲神经性厌食症相关的特定儿童疾病的风险.
- 为了告知潜在的支持策略,精神性厌食症的母亲.
主要方法:
- 一项回顾性队列研究,涉及1,269,370名儿童在北克,加拿大 (2006-2022).
- 暴露被定义为母亲的神经性厌食症,需要住院治疗.
- 儿童因精神,物质相关或神经发育障碍 (出生至17岁) 住院治疗是主要结果.
- 考克斯回归模型用于估计危险比率 (HR) 和95%置信区间 (CI).
主要成果:
- 患有神经性厌食症的母亲的孩子因精神问题,与物质有关的问题和神经发育问题的住院率较高 (1000人中有104.7人 vs 51.4人).
- 对精神卫生住院患者,特别是神经性厌食症 (HR 10.62) 和焦虑/压力障碍 (HR 1.84) 发现了显著的关联.
- 母亲性神经性厌食症也与儿童中与物质相关 (HR 2.01) 和神经发育性发病率 (HR 1.55) 的风险增加有关.
结论:
- 母亲性神经性厌食症与儿童因精神,与物质有关的和神经发育条件的住院病例增加有关.
- 虽然结果很重要,但潜在的混因素需要谨慎解释.
- 患有神经性厌食症的母亲可以从增强的心理社会支持中受益,以减轻后代的发病率.
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