在低血量患者的辅助呼吸监测
Alessandro Cardu1,2, L Felipe Damiani3, Tommaso Rosà2,4
1Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
在低血量呼吸衰竭患者中,平衡呼吸机支持和患者的努力至关重要. 监测呼吸机制和肺压力有助于预防自发呼吸期间的肺损伤,指导安全的侵入性通风.
科学领域:
- 关键护理医学 关键护理医学
- 呼吸系统生理学 呼吸系统生理学
- 机械通风机械通风机械通风
背景情况:
- 在低血量呼吸衰竭和ARDS的辅助通风中,在呼吸器支持和患者努力之间取得平衡是必不可少的.
- 当代方法鼓励自发呼吸,同时避免过度的吸入力,以防止肺部或隔膜受伤.
- 自发呼吸在轻度至中度的低氧化症中是有益的,但在中度至重度的病例中可能是有害的,特别是在低呼吸系统遵守的情况下.
研究的目的:
- 在低血量患者的侵入性通风过程中提供安全有效的自发呼吸监测技术的实用概述.
- 解释监测呼吸驱动,努力,机械和肺部压力的背后的生理学理由.
- 引导临床医生检测和管理有害的膨胀模式,并预防自我造成的肺损伤.
主要方法:
- 对终端呼吸道阻塞的第一次努力进行分析,以评估呼吸驱动力 (P0.1) 和吸入力 (ΔPocc).
- 测量平原压力以估计肺部总压力,并计算呼吸系统的符合性和驱动压力.
- 床边监测技术集成,以全面了解患者的呼吸机制和工作量.
主要成果:
- P0.1最佳范围:1-4cmH2O用于呼吸驱动强度.
- ΔPocc最佳范围:5-14cmH2O用于吸入力.
- 驾驶压力>12cmH2O与死亡率增加有关.
结论:
- 监测呼吸驱动,努力,机械和肺压力对于防止侵入性通风期间自我造成的肺损伤至关重要.
- 床边测量P0.1,ΔPocc和驱动压力,为患者与呼吸机的相互作用和肺部压力提供了关键的见解.
- 整合这些监测技术使得低血症患者的自发呼吸能够安全有效地维持.
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