怀孕期间的维生素D水平和后代的牙损伤
Nuo Xu1,2, Zexin Chen1,2, Boya Wang1,2
1Department of Public Health, and Department of Anesthesiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
JAMA network open
|December 2, 2025
概括
怀孕期间母亲的维生素D水平与后代患幼儿食 (ECC) 的风险较低有关. 保持足够的维生素D状态可能有助于预防儿童的牙损伤.
科学领域:
- 产科和妇科 产科和妇科
- 儿科牙科 儿科牙科
- 营养科学 营养科学
背景情况:
- 怀孕期间母亲的维生素D水平与后代的早期儿童 (ECC) 有着不一致的联系.
- 了解这种关联对于母婴健康战略至关重要.
- 需要进一步的研究来澄清母亲维生素D对后代牙健康的三个月特异性影响.
研究的目的:
- 评估不同怀孕季度母亲维生素D状况与后代牙损伤发病率之间的关联.
- 研究母亲的25-氧维生素D (25[OH]D) 水平与儿童早期 (ECCs) 之间的关系.
主要方法:
- 一项前性队列研究,涉及4109对来自舟山孕妇队列的母子对.
- 每个三个月测量母亲的血25-氧维生素D (25[OH]D) 水平.
- 评估了后代早期儿童 (ECC),腐烂,缺失或填充牙 (dmft) 指数,以及率.
主要成果:
- 较高的母体25...OH) D水平与所有三个月的后代ECC的几率降低有关.
- 孕产妇维生素D缺乏 (VDD) 与ECC的概率增加有关,尽管一些关联在纠正后减弱了.
- 增加的母体25~OH) D水平与较低的dmft得分和后代的空率相关.
结论:
- 在整个怀孕期间,母亲的25OH) D水平与后代ECCs的风险有相反的关联.
- 这些发现表明,怀孕期间补充维生素D有潜在的益处,可以减少儿童牙损伤.
- 优化母亲的维生素D状况可能是预防幼儿的可行策略.
更多相关视频
08:12Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
10.6K
06:47Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
9.8K
相关概念视频
01:25Role of Vitamins in Maintaining Bone Health
4.9K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
4.9K
01:23Role of Skin in Vitamin D Synthesis
7.4K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.4K
01:15Teeth
1.6K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
1.6K
01:30Vitamins
2.2K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
2.2K
01:21Tooth Anatomy
1.9K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
1.9K
01:31Essential Minerals for Bone Health
5.9K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
5.9K