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Updated: Jan 9, 2026

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瘤性KRAS/ERK/JUNB信号抑制了胰腺癌中的GATA6分化调节器

Zheng Zhong1, Xinang Cao2, Pei-Ju Liao1

  • 1Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore.

The Journal of clinical investigation
|December 2, 2025
PubMed
概括

瘤性KRAS激活的ERK通路抑制了胰腺癌中的GATA6转录. 抑制这种途径增加了GATA6,提高了化疗的有效性,并提供了一个新的治疗策略.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学在瘤学瘤学.信号传导传导是指信号的传导.

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