免疫能力强的儿童的HHV-6脑炎后的神经心理症状:一个病例报告
Dima Habanjar1, Samah Trad1, Daniel Charouf1
1Division of Pediatric Neurology, Department of Pediatrics and Adolescent Medicine, American University of Beirut, Beirut, Lebanon.
The American journal of case reports
|December 2, 2025
概括
人类疹病毒6 (HHV-6) 脑炎可能会导致神经精神病症症状,如在免疫能力较强的儿童. 这种罕见的介绍突显了对HHV-6中枢神经系统感染的认识和及时诊断的需要.
科学领域:
- 儿科神经学 儿科神经学
- 传染性疾病 传染性疾病
- 神经精神病学是一种神经精神病学.
背景情况:
- 人类疹病毒6 (HHV-6) 通常会在免疫功能低下的个体中引起婴儿和脑炎.
- 免疫能力不足儿童的HHV-6脑炎很少见,通常是自我限制的,有神经症状如发作报告,但神经精神问题,特别是catatonia,是非常罕见的.
研究的目的:
- 报告第一个HHV-6中枢神经系统感染的病例,该病例与神经精神疾病表现,特别是超运动性,在一个免疫能力强的儿童中呈现.
- 突出显示HHV-6脑炎是儿童急性神经精神病症状的潜在原因,即使没有典型脑炎症状.
主要方法:
- 病例报告:一个4岁的免疫能力强的男孩在病毒感染后突然改变了行为.
- 脑脊髓液测试证实HHV-6阳性.
- 临床评估包括对白色炎的评估,自身免疫性脑炎的检查,MRI和EEG.
主要成果:
- 患者表现出高动力性猫症的症状,包括焦虑,易怒,强迫性行为,反应能力降低和失眠.
- 脑脊液测试对HHV-6呈阳性;自身免疫检测呈阴性.
- 用甘西克洛维尔和洛拉泽治疗导致了显著的临床改善,随访时几乎完全康复.
结论:
- 该病例代表了首次记录的HHV-6中枢神经系统感染病例,导致神经精神病症状,包括儿科免疫能力强的儿科患者的猫头.
- 在儿童急性神经精神疾病的差异诊断中应考虑HHV-6脑炎.
- 识别这种罕见的呈现对于及时诊断和有效管理至关重要.
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