成年患者的睡眠障碍和术后妄想之间的关系:更新系统综述和元分析的议定书
Qianli Huang1,2, Changhui Shao3, Ling Peng1
1Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
PloS one
|December 2, 2025
概括
这一系统性审查将调查成年人睡眠障碍和术后妄想 (POD) 风险之间的联系. 研究结果旨在澄清这种关联,以改善有关患者睡眠健康的临床决策.
科学领域:
- 医学研究 医学研究
- 临床流行病学临床流行病学
- 系统审查和元分析.
背景情况:
- 手术后妄 (POD) 是一个常见的手术并发症.
- 睡眠障碍与POD风险之间的关系是有争议的,有相互矛盾的证据.
- 睡眠障碍越来越多地被认为是POD的潜在危险因素.
研究的目的:
- 系统地审查和对现有的观察性研究进行元分析.
- 为了估计睡眠障碍与成人患者的POD风险之间的关联.
- 为临床实践提供基于证据的见解.
主要方法:
- 在PubMed,Embase,CINAHL和PsycINFO数据库中进行系统的文献搜索.
- 包括调查睡眠障碍和POD的观察性研究.
- 随机效应模型用于聚合风险估计,具有子组和灵敏度分析.
- 偏见风险评估和包含的研究的质量评估.
主要成果:
- 本节将介绍睡眠障碍与POD之间的关联的综合风险估计.
- 通过子组分析将探索异质性.
- 出版偏差将使用漏斗图和埃格尔测试进行评估.
结论:
- 系统性审查和元分析将澄清睡眠障碍与POD风险之间的关联.
- 结果将为临床实践提供信息,帮助手术患者做出更好的健康决策.
- 这项研究有助于了解睡眠在术后结果中的作用.
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