新的皮里米丁-阿尔图酸混合物通过附带敏感度克服非小细胞肺癌中的多药性耐药性

Ljiljana Koračak1, Vladimir Ajdačić1, Milica Selaković1

  • 1Innovative Centre, Faculty of Chemistry, Ltd., Studentski trg 12 - 16, 11158 Belgrade, Republic of Serbia.

Bioorganic chemistry
|December 2, 2025
PubMed
概括

新的pyrimidine-artesunate混合化合物显示出对抗耐药性非小细胞肺癌 (NSCLC) 的承诺. 这些混合体表现出附带敏感性,通过抑制P-糖蛋白 (P-gp) 来选择性向多药耐药癌细胞.

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