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Updated: Jan 9, 2026

Brain Slice Biotinylation: An Ex Vivo Approach to Measure Region-specific Plasma Membrane Protein Trafficking in Adult Neurons
06:18

Brain Slice Biotinylation: An Ex Vivo Approach to Measure Region-specific Plasma Membrane Protein Trafficking in Adult Neurons

Published on: April 3, 2014

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通过基于物理的建模和实验验证的实验验证,发现了人类多巴胺载体的新型全抑制剂

Xiaolong Ye1, Shengzhe Deng2, Ding Luo1

  • 1School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, China.

European journal of medicinal chemistry
|December 2, 2025
PubMed
概括

研究人员发现了一种新的全抑制剂,DAM-001,用于人类多巴胺转运体 (hDAT). 这一发现为开发潜在副作用较少的中枢神经系统疾病治疗方法提供了一种新的策略.

关键词:
阿洛斯特里克遗址多巴胺运输体是多巴胺的运输体.药物设计 药物设计分子动力学模拟模型虚拟选是一个虚拟的选.

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