流动性作为PEGylated脂质纳米颗粒中稳定性的关键决定因素,这些纳米颗粒载有TLR7激动剂

Carmen Palomino-Cano1, M Carmen Mera-Delgado1, Ramon Pons2

  • 1Department of Pharmaceutical Sciences, School of Pharmacy and Nutrition, University of Navarra, c/Irunlarrea 1, Pamplona 31008, Spain.

概括

研究人员开发了基于脂质的纳米载体 (LNCs),以安全地提供imimquimod (IMQ),一种TLR7激动剂. 优化的LNC配方增强了IMQ传递和重新编程的免疫细胞,突出了纳米载体设计,以获得更安全的免疫疗法.

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