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发生率,死亡率和经济负担的败血症在瑞士,2019-2023年:一个全国性的基于人口的分析
Nora Luethi1, Tapio Niemi2, Olga Endrich3
1Department of Intensive Care and Neonatology, and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
概括
败血症是瑞士的主要健康问题,发病率稳定,但死亡率高,成本增加. 目前的编码方法低估了其真正的负担,需要更好的监督和定义,以制定有效的政策.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 卫生经济学 卫生经济学
背景情况:
- 败血症是一个重要的,经常被低估的公共卫生挑战.
- 准确量化败血症趋势对于有效的医疗保健规划和资源配置至关重要.
研究的目的:
- 分析瑞士血症发病率,死亡率,医疗保健利用率和直接医院费用的国家趋势.
- 评估不同编码方法 (明确与隐性ICD-10) 对败血症负担估计的影响.
主要方法:
- 全国对瑞士急性护理医院2019-2023年出院数据进行了回顾性分析.
- 使用显式和隐式ICD-10代码进行败血症识别.
- 评估发病率,死亡率 (住院,30日,180日,360日),资源使用和直接医院费用.
主要成果:
- 已确定超过50万例败血症病例 (明确和隐含编码).
- 观察到稳定的发病率和死亡率,新生儿和老年人负担最高.
- 在2023年,隐性败血症的年龄标准化发病率达到每10万人中963人;住院死亡率为每1000人中189人. 年费用超过107亿瑞士法郎.
结论:
- 败血症在瑞士是一个巨大的和低估的负担,其特点是高死亡率和不断上升的成本.
- 仅仅依赖明确编码显著低估了败血症的真正范围.
- 综合监测系统和统一的定义对于准确的影响评估和政策制定至关重要.
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