后COVID综合征的持续睡眠症状:巴西前性临床研究
Alissa Elen Formiga Moura1,2, Danilo Nunes Oliveira1,3, José Wagner Leonel Tavares Júnior1
1Universidade Federal do Ceará, Hospital Universitário Walter Cantídio, Departamento de Neurologia, Fortaleza CE, Brazil.
Arquivos de neuro-psiquiatria
|December 2, 2025
概括
后冠状病毒疾病 (COVID) 综合征经常导致持续的睡眠问题,如失眠和高睡眠症. 患有失眠的COVID-19患者的认知投诉也更高,这表明潜在的长期神经效应.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 传染性疾病 传染性疾病
背景情况:
- 后冠状病毒疾病 (COVID) 综合征,以SARS-CoV-2感染后的持续症状为特征,显著影响睡眠质量.
- 在COVID-19患者中,睡眠障碍是由于直接的病毒影响,改变昼夜节律,隔离程序和社会隔离引起的.
研究的目的:
- 为了调查睡眠障碍和认知投诉的长期持久性在一个年后患有后冠状病毒疾病 (COVID) 综合征的患者.
- 重新评估COVID-19后经历睡眠相关症状的个体的睡眠模式和神经功能.
主要方法:
- 一个观察性,纵向的,前性临床研究,涉及两个评估阶段,隔一年.
- 参与者填写了经过验证的问卷,包括老年抑郁量表 (GDS),贝克清单,阿登布鲁克认知检查 - 修订 (ACE-R) 和迷你精神状态检查 (MMSE).
- 睡眠障碍评估使用了通过结构化问卷的综合临床病史.
主要成果:
- 在重新评估的39名患者中,23.07% (9名患者) 继续患有失眠症,5.12% (2名患者) 患有持续的中央高睡眠症.
- 在持续的失眠和较高的认知投诉率 (56%,p=0.001) 之间发现了显著的关联.
结论:
- 在冠状病毒病后 (COVID) 综合征患者中,失眠和中央高睡眠症持续存在,这表明潜在的中枢神经系统可能会长期受到损害.
- 持续跟踪和管理睡眠和认知障碍对于长期COVID患者至关重要.
更多相关视频
相关概念视频
Substance Use Disorders Affecting Sleep
369
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
369
REM Sleep Behavior Disorder
1.3K
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
1.3K
Narcolepsy
466
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
466
Sleep-Wake Cycles
2.7K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
2.7K
Management of Insomnia
507
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
507
Insufficient Sleep and Sleep Deprivation
807
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
807


