用于MALDI-2MS的臭氧化成像,在生物组织中对酸乙醇胺的碳-碳双键定位异构体进行成像

Dominika Bezdeková1, Michal Hendrych2, Jan Schwenzfeier3

  • 1Department of Chemistry, Faculty of Science, Masaryk University, Brno, Czech Republic.

Analytica chimica acta
|December 2, 2025
PubMed
概括

这项研究引入了MALDI-2激光后电离,以改善组织中酸乙烯胺 (PE) 的成像. 改进的方法成功地绘制了小鼠胚胎和人类癌症中的位置性脂质异构体,揭示了不同的空间分布和潜在的代谢作用.

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